For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips.


Key Features
Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource.
Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis.
Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases.
Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases.
Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci.
PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America.
Includes regular updates online for the life of the edition.
Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition.
Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips.


Key Features
Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource.
Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis.
Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases.
Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases.
Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci.
PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America.
Includes regular updates online for the life of the edition.
Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition.
Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

Lymphoepithelioma-like carcinoma (LELC) is an uncommon variant of squamous cell carcinoma, which is histologically identical to lymphoepithelial carcinoma of the nasopharynx. LELCs have been reported at a variety of sites, including the stomach, salivary gland, thymus, cervix, endometrium, breast, skin, bladder, and lung. We report 2 LELCs of the vagina and 1 of the anal canal, the first report of LELC at the latter site. All 3 neoplasms were diffusely positive with p16 (block-type immunoreactivity) and the anal canal lesion contained high-risk human papillomavirus type 16; the 2 vaginal neoplasms underwent human papillomavirus testing but were unsuitable for analysis. All cases were Epstein-Barr virus negative. In reporting these cases, we highlight the potential for misdiagnosis and suggest an association with human papillomavirus infection similar to LELCs in the uterine cervix.

Initialement centrée sur la prévention et le contrôle des maladies infectieuses, la surveillance épidémiologique a connu un essor considérable en France depuis une vingtaine d'années, devenant l'un des axes majeurs de l'action en santé publique. Les grandes affaires de santé publique survenues récemment (sang contaminé, canicule, pandémie grippale...) ont d'ailleurs bien montré la nécessité de pouvoir disposer d'un système de surveillance efficace, fiable et réactif. Premier ouvrage en langue française spécifiquement consacré à ce sujet, Surveillance épidémiologique a pour objectifs de faire connaître aux professionnels de santé les principes des systèmes de santé existants, de fournir aux épidémiologistes et chercheurs des outils méthodologiques, de permettre aux étudiants et enseignants de disposer d'un manuel complet et précis et enfin d'apporter aux décideurs en santé publique des informations de référence. L'ouvrage est organisé en quatre grandes parties, dans lesquelles sont développés : les principes généraux et l'organisation de la surveillance épidémiologique ; les méthodes et théories spécifiques à ce domaine, avec un souci constant d'accessibilité pour les non-spécialistes ; les différents champs d'application (pathologies ou groupes de population particuliers...) ; les relations de la surveillance épidémiologique avec les autres domaines de la santé publique (prévention, réglementation, aspects sociopolitiques...). Une attention particulière a également été portée à la surveillance en santé internationale.
L'ouvrage, agrémenté de nombreux graphiques et tableaux, est complété par une série de fiches techniques expliquant et définissant les notions fondamentales de l'épidémiologie descriptive. Il intéressera tous les médecins, chercheurs, enseignants et étudiants en santé publique ainsi que tous ceux en charge de la santé publique, de la surveillance ou de la prévention dans les agences ou organismes publics et dans les réseaux de professionnels.